Sr. Scientist (Neuroimmunology) - 37079

Company: Freyr
Location: Cambridge
Posted on: June 3, 2025

Job Description:

Position Details:

Scroll down the page to see all associated job requirements, and any responsibilities successful candidates can expect.

Job ID: 37079
Duration: 12 months
Shift: Monday-Friday, 8:00 AM-5:00 PM EST
Benefits: Paid sick days, 401k, discounted health insurance

Full Job Description:

Qualifications:
Education and Experience:
BS/BA degree in Biology, Neuroscience, Molecular Biology Bioengineering, Biotechnology or equivalent degree with at least 2+ years of industry or academia experience

Required skills and competencies:
--- Strong general knowledge of cell culture methods and sterile technique
--- Experience working with immortalized cell lines, primary rodent neurons and glia (e.g. microglia), and human iPS-derived CNS cell models including microglia and neurons
--- Understanding of standard cell transfection techniques using lipid-based and electroporation methodology
--- Cell staining methods including Immunofluorescence and cell masks or cell structural staining methods
--- Some experience with method optimization, troubleshooting and strong critical thinking skills
--- Proven experience in image acquisition and strong microscopy skills
--- Strong working knowledge of mouse neuroanatomy
--- Ability to work independently on data analysis including practical knowledge of statistics

Preferred skills:
--- Experience with plate-based high content imaging microscopy
--- Live cell imaging experience
--- Demonstrated experience with quantitative image analysis
--- Working understanding of biochemical and molecular biology techniques including protein and RNA extraction, quantitation and detection methods (western blot, ELISA, qPCR)
--- Experience with cellular signaling and functional studies including phagocytosis and/or cell motility measures
--- Strong oral, written and presentation skills with ability to explain concepts clearly in lab and small team settings

Responsibilities:
The Neuroimmunology team is seeking a motivated and technically-skilled individual with strong CNS cell biology skills to join our Cambridge-based team. Candidates will be able to collaborate with colleagues across diverse functional areas including genetics, chemical biology, immunology and pharmacology.

Primary responsibilities include:
--- Culturing of stable cell lines, primary and iPS-derived microglia to support study of disease-associated functions and phenotypes
--- Assist in developing and performing disease-relevant cell-based functional assays
--- Perform high content imaging, biochemical and molecular profiling techniques
--- Support identification and validation of novel therapeutic targets to treat neurodegenerative diseases
--- Communicate data clearly and concisely to appropriate teams and stakeholders
--- Thrive in a team environment

Regards,
Vinay Shastri
Senior Associate - Pharmaceutical Recruitment
Phone: +1 609 681 2410
Email: vinay.shastri@freyrsolutions.com
150 College Road West, Ste 102, Princeton, NJ 08540
www.freyrsolutions.com

Keywords: Freyr, Middletown , Sr. Scientist (Neuroimmunology) - 37079, Other , Cambridge, Connecticut