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Director/Principal Scientist - Protein Kinase Assays

Company: Bevov
Location: Middletown
Posted on: July 15, 2021

Job Description:

Job Description

Our client has an exciting Life Science opportunity to join our rapidly growing team developing novel protein Kinase activity assays and offering Custom Testing Services that enable our clients. Their innovative and patented fluorescence-based sensor technology is exclusively licensed from MIT.

Responsibilities

  • Highly motivated and self-driven - Thrive in a fast-paced and interdependent working environment.
  • Excellent technique including small volume dispensing and strong attention to detail.
  • Design and develop biochemical assays to identify and characterize small-molecule modulators using a variety of techniques and detection methods
  • Ability to master new techniques, find solutions and effectively multitask to achieve goals efficiently.
  • Strong computer skills including Microsoft Office/Access and scientific/data analysis software.
  • Guide and develop laboratory-based scientists focused on the design and conduct of fluorescence-based assays to support discovery and definitive development assays for regulatory filings.
  • Perform enzyme kinetic analyses to characterize biological enzyme systems including kinases.
  • Demonstrated organizational, documentation, and oral communication skills with the ability to work independently and as a team.
  • Practical knowledge of fluorescence-based activity assays to assess enzyme kinetics and drug potency.

Qualifications

  • Bachelor's or advanced degree in biology, chemistry, biochemistry, etc.
  • 8-20 years hands-on lab experience developing or using quantitative microtiter plate-based assays and also successful leading teams of 5-10 people with clear drive, energy, and vision to allow them to accelerate company growth.
  • Requires demonstrated proficiency working at the bench with expertise in enzymology, routine assessments of small molecule compound potency and drug mechanism of action using fluorescence-based assays run in 384-well microplate reader formats. 
  • Needs to also be proficient in data analysis using Graph Pad Prism or related software. 
  • Familiarity with modern automation instrumentation and software for drug discovery assays.
  • Industry experience with demonstrated productivity analyzing enzyme inhibitors.
  • Demonstrated ability to work well with other accomplished professionals within and across functions/teams. Willing collaborator.
  • Strong written and oral communication skills.
  • Ability to multi-task and shift priorities rapidly to meet tight deadlines.

Benefits

Our client is an Equal Opportunity Employer (EOE) and strongly supports diversity in the workplace.

Keywords: Bevov, Middletown , Director/Principal Scientist - Protein Kinase Assays, Other , Middletown, Connecticut

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